Technical Name |
ISOPROPYL-D-GLUCOPYRANOSIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF |
Project Operator |
National Tsing Hua University, |
Project Host |
陳令儀 |
Summary |
This invention relates to a new chemical compound of Isopropyl-D-glucopyranoside derivatives and its total synthesis to prepare the chemical compound. The invention also provides uses of the Isopropyl-D-glucopyranoside derivatives for promoting regeneration of injured brain neurons and retinal neurons. In addition, the Isopropyl-D-glucopyranoside derivatives can promote recovery motor function deficit . |
Scientific Breakthrough |
There is currently no drug to promote nerve repair for patients suffer from brain injury. The invention relates to a new chemical compound of Isopropyl-D-glucopyranoside derivatives and its total synthesis to prepare the chemical compound. The invention also provides uses of the Isopropyl-D-glucopyranoside derivatives for promoting regeneration of injured brain neurons and retinal neurons. In addition, the Isopropyl-D-glucopyranoside derivatives can promote recovery of motor function deficit. |
Industrial Applicability |
Higher than 60% patients with traumatic brain injury are young and mid-age adults. Early treatment of these patient largely reduces neuronal death due to chronic inflammation. Moreover, the use of this invention would reduce the risk for developing neurodegenerative diseases. This invention is intended to be used in medical center to treat motor function deficit caused by traumatic brain injury. |
Keyword |
Traumatic brain injury Nerve repair Total synthesis of chemicals Motor coordination Neurite outgrowth Recovery of motor function Pharmaceutical composition Retinal regeneration Cortical neuron regeneration recurrent lung cancer |