Mental illnesses cause accelerated brain aging as they progress. Professor Albert Yang＇s team discovered distinct degeneration trajectories in different brain regions and developed a method to precisely quantify degeneration at various ages and stages of mental illness. This technique, applied to schizophrenia, bipolar disorder, and major depressive disorder, establishes a platform for tracking personalized brain degeneration and is used in clinical services at Taipei Veterans General Hospital.

Mental illnesses cause accelerated brain aging as they progress. Professor Albert Yang＇s team discovered distinct degeneration trajectories in different brain regions and developed a method to precisely quantify degeneration at various ages and stages of mental illness. This technique, applied to schizophrenia, bipolar disorder, and major depressive disorder, establishes a platform for tracking personalized brain degeneration and is used in clinical services at Taipei Veterans General Hospital.

Professor Albert Yang＇s team developed a method to quantify brain degeneration in mental illnesses, incorporating age of onset and disease progression. Applied to schizophrenia, bipolar disorder, and depression, we modeled 138 brain regions to predict and track abnormalities. Published in top journals and patented in the U.S., the research shows significant brain degeneration, identifying key regions like the insula, inferior frontal gyrus, or anterior cingulate gyrus, aiding precise diagnosis.