The acoustic vortex light guide tech uses ultrasonic waves to form bubble structure for non-contact, dynamic control, reversibility, and reduced light scattering. By employing acoustic vortices, it minimizes tissue scattering, increasing light fluence by about 34.3%. Simple to operate, non-invasive, and lowering tissue damage risks, it offers a novel solution for biomedical optical diagnostics and therapy.

This technique utilizes acoustic vortex technic to reduce light scattering by creating a bubble tunnel. Ultrasonic waves induce bubble formation via inertial cavitation. The structure of acoustic vortices forms an optical lens structure, restricting light scattering. By dynamically adjusting ultrasonic parameters, this method can dynamically control light propagation. This work was presented at the 2022 International Ultrasonics Symposium and patented in Taiwan, the US, and PCT was under review.

The acoustic vortex light guide system combines non-invasive, reversible, and tissue-friendly characteristics. Applying it in photothermal therapy and photogene therapy can reduce light scattering in tissues, enhancing treatment efficacy. This addresses issues like inadequate treatment depth and energy, offering potential clinical applications.