| Technical Name | Production of zebrafish disease models for anti-aging drug screen by genome editing | ||
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| Project Operator | Chung Yuan Christian University | ||
| Project Host | 蕭崇德 | ||
| Summary | Our research team has been working on the research project related to progeroid syndrome and successfully established the first zebrafish disease model simulating the human progeroid syndrome with deficiency of pycr1 gene. The establishment of the zebrafish progeroid model be beneficial to applications in academic and clinical research. In the future this model can serve to study the progeroid syndrome related mechanism and assist us in screening the therapeutic drugs. |
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| Scientific Breakthrough | Our research team has been working on the research project related to progeroid syndrome and successfully established the first zebrafish disease model simulating the human progeroid syndrome with deficiency of pycr1 gene. |
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| Industrial Applicability | The establishment of the zebrafish progeroid model be beneficial to applications in academic and clinical research. In the future this model can serve to study the progeroid syndrome related mechanism and assist us in screening the therapeutic drugs. |
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| Keyword | Aging Zebrafish Genome editing Drug screen proline mitochondria metabolism Animal behavior anxiety Circadian rhythm | ||
- cdhsiao@cycu.edu.tw
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