An innovative ointment solves an unmet clinical need to cure keloid wounds The composition of the ointment can precisely modulate the cell functionsgene expression of keloid fibroblasts, making them close to the performance of normal fibroblasts. Thereby, when applying the ointment to keloid woundsthe human body prone to the formation of keloid wounds, the wound is smoothed, healing close to normal skin.

We develop smart fabrics by electrospinning crystallinity-modified self-healing materials, which are facilitated by the reversible physical crosslinking between poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP)ionic liquid. The fiber morphology can be maintained without losing the fibrous structure. The fabrics can achieve the healing effects without the need of seamingany adhesive. The fabrics are waterproofbreathable. By printing electrically conductive channels using ionic liquid, capacitive pressure sensorsresistive tensile sensor arrays are fabricated.

Our results have demonstrated that our tissue gel can effectively promote angiogenesiswound healing in diabetic wounds. Our product prototype will be a powerful therapeutic product to treat diabetic foot ulcersgo further to rescue diabetic patients from amputation.

The bioactive corecorona synergism of sub-nanometer gold enables slowed inflammationincreased tissue regeneration in wound hypoxia. The developed dual-function wound dressing based on a gold nanocluster with a plane structurean adhesive layer presented two features: (1) the gold nanocluster can attenuate the inflammatory response by adjusting the strength of the active site (i.e., l

A novel “Platform Technology” in surgical hemostasis, based on biodegradable polyurethane particles with anti-inflammatory and nerve repair, not only accelerates wound healing but also provides solutions for hemostasis during surgery, and improve biocompatibility and adverse of commercially hemostats to achieve the best patient care. Our first product is aimed to provide a hemostatic agent, use on the bleeding surface and deep, with additional functions to surgeons, which allows customers to shorten the operation time, reduce stay in the hospital, and reduce the chance of secondary surgery.

"1. New method to prepare (3S, 3’S)astaxanthin, with high yield, high stabilityharmless to organism 2. The method has variety of biological activities anti-oxidation, anti-agingpromote damage tissue repair 3. It has anti-cancer potential, especially effective against metastatic cancer cells 4. Applied as Multifunctional medical supplies, functional foods, functional drinks, cosmeticsmaintenance products"

This work synchronizes electrocardiograph to narrow-band imaging with high-power lens to observe the micro-circulation on the skin. The time difference among the arrivals of the cardiac pulse wave on different parts of the path is then used to calculate the pulse wave velocity of the arteries, providing very helpful diagnosis of diseases closely related to the peripheral circulation.

We developed Polypyrrole (PPy) based NIR-photothermal related platform technologies. This photothermal driving hyperthermia carrier systems are biocompatible are able to possess versatile functions in anticancer, antibacterial, thrombolysis, wound-healingsuppression of inflammation related bioengineering potential applications. These innovative works shed light on the efficacy of combining photothermal-performance with translational manner in biomedical, clinicalindustrial designs.

The self-healing ultra-high-performance concrete is a green construction material. It has the key characteristics of self-healing ability, high deformability, and ultra-high strength. The material composition contains a high proportion of by-products from industrial manufacturing. The particle packing density of the developed material is optimized to make this new multi-functional concrete material also have the ability of self-healing and deformability.

Image that your cell phone can be self-poweredable to self-healing after damagerobots in Sci-fi movie have self-poweredself-healable skins. Here, we present the first energy-harvesting triboelectric artificial skin that is entirely, intrinsically,autonomously self-healablesimultaneously highly transparentextraordinarily stretchableable to drive via self-generating

Epidermolysis bullosa (EB) is an inherited blistering skin diseaseis also one of the most "urgent, severe, difficultrare" diseases. Since there are at least 21 disease-causing genes involved in EB with markedly variable manifestations, it is particularly difficult for accurate diagnosis. In recent years, next generation sequencing (NGS) has been widely applied in the genetic diagnosis of rare hereditary disorders. The EB team in NCKU established the protocol of EB diagnosis by combining NGSvarious tools of pathologymolecular studies. Till now, we have completed the genetic diagnosis for more than 50 Taiwanese EB patients.

Our PEDD has been used to detect the HNE level in both tearwound fluids of 9 patients,the limitations of detection were about 0.76 μg/mL0.63 μg/mL respectively. Our device requires only 15 minutes, 3 μL of clinical sample for each test,offers superior sensitivity compared to other current HNE detection methods. The HNE concentrations in the patient samples have shown that the elevated HNE levels might suggest an abnormal healing of either acutechronic wounds, consistent with previous studies that showed excess protease levels in all non-healing wounds.

Chronic wound infection is a leading cause of mortality in injured patients worldwide. At present, available systemic antibiotic treatments have an insufficient tissue penetration ability and allow the development of antibiotic-resistant pathogens. The identification of therapeutic agents with wound healing and antimicrobial functions is necessary to heal the wound and cure infections. Our report shows that the antimicrobial peptide (AMP) Epinecidin-1 (Epi-1) efficiently heals MRSA-infected heat burn injuries and provides protection from infection in mouse and pig model. Our results demonstrate that the biomaterial Epi-1 heals wounds through increasing epithelial cell proliferation, vascularization, and the formation of collagen and controls MRSA infection-mediated sepsis in pigs.

Directly writing 3D structures into supporting mediums is a relatively new developing technology. The liquid-like solid (LLS) materials are developed as supporting mediums, that possesses the self-healing ability and tunable yield stress. Because the components of this emulsion glass are mostly water and oil, it exhibits chemical stability when exposed to UV radiation and high temperature. Based on the above features, this emulsion glass can be regarded as a new kind of LLS material for supporting mediums.

The aim of this study was to develop of high safety, high performance sulfide-based all-solid-state Li-ion battery (ASSLIB). The ASSLIB composes of a flexible, high ionic conductive,moisture insensitive sulfide-based solid-state electrolyte (SSE) film, Si/C composite anode material with self-healing polymer binder, high capacity LiNi0.8Co0.1Mn0.1O2 (NMC811) composite cathode,garnet-in-polymer solid composite interlayer to prevent decomposition of sulfide-based SSE with electrode materials.