3D digital pathology imagingAI auxiliary diagnosis platform integrates 3D pathology sample preparation, high speed image scanning,intelligent software analysis into a novel system. We have collaborated with clinical pathologists to develop both 3D biopsy pathology imaging workflowthe world first 3D pathology image analysis software MetaLite, along with AI models pathology feature annotationquantitative analysis of solid tumor with high accuracy can be rapidly processed. We have transferred patented technology to start up JelloX Biotech Inc. at NTHU for further operation.

We use features such as asymmetric expression and crooked eyes to assess the risk of facial stroke. Observing the micro vibration of the head caused by the contraction of the heart, and develop a zero-contact facial heart rate and respiration rate detection technology in conjunction with the camera. The technology can accurately measure heart rate and respiration rate in real time, thereby reducing the risk of infection. This technology has obtained two ROC patents (M590433, I689285), two US patents (HEART RATE DETECTION METHOD AND DEVICE THEREOF,MOUTH AND NOSE OCCLUDED DETECTING METHOD AND SYSTEM THEREOF). The possibility of detecting strokes through AI machine learning methods is not only accurate, but also find out signs of stroke early to grasp the best time to seek medical treatment.

We propose an AI dynamics drug repurposing platform applicate on COVID-19. This platform analyzed a large number of structures of SARS-CoV, MERS,cross-species coronavirus 3CL protease-ligand complexes to construct uncovering six flexible active site conformationspharmacophore clusters for SARS-CoV-2 3CL protease screening all FDA drugsfound four inhibitors within three months. Among them, JM206 had even demonstrated ten times better efficacy than Remdesivir in-vitro assayalso show the effect on the in-vivo hamster model to alleviate the symptoms caused by COVID-19.