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The core concept of the decision support system is to establish machine learning-based predictive modelsenable their interpretability to support physicians making clinical decisions in practice. The developed technique is part of the capstone project named "Smart Emergency Department," sponsored by the Ministry of ScienceTechnology. The system comprises NTUH (National Taiwan University Hospital) EMR (Electronic Medical Record) importance analysis, accurate clinical quality indicator prediction,similar medical record retrieval. It is expected to improve the patients＇ flowalleviate emergency department crowding. It has been verified in retrospective studieswill officially enter the clinical trial phase this year.

The proposed technologies apply deep learning methodsbig clinical data for lung cancer decision support. The system consists of: 1) CT radiogenomicspatho-genomics for automatic cancer detectionprediction of EGFR mutation 2) demographics to predict survival 3) genomics to predict cancer recurrencemetastasis,4) drug response inference for the best target therapy option. The modules are constructed on an AI-based Clinical Decision Support System (CDSS-SDM). The system is expected to provide physicianspatients with personalized medication recommendations.