Based on our long-term accumulated healthy brain image database, we used meta-analysismultivariate analytical algorithms to extract the cognitive biological characteristics of individual subjects. By using machine learning / artificial intelligence algorithms, these features were further calculated for capturing individual cognition according to related brain networks. This biological index could be a potential marker for evaluating individual brain health, cognitive functions,risk for neurodegenerative diseases.

The Al-based web diagnostic system provides an online assessment tool for diagnosing schizophrenia. The Explainable Deep Neural Network classifier is deployed to analyze gray matterwhite matter to derive diagnostic classification of schizophrenia. The structural brain abnormalities associated with schizophrenia is visualized on the AI-based web diagnostic system at individual level.