We developed Polypyrrole (PPy) based NIR-photothermal related platform technologies. This photothermal driving hyperthermia carrier systems are biocompatible are able to possess versatile functions in anticancer, antibacterial, thrombolysis, wound-healingsuppression of inflammation related bioengineering potential applications. These innovative works shed light on the efficacy of combining photothermal-performance with translational manner in biomedical, clinicalindustrial designs.

Current mainstream pharmacotherapy of glaucoma is the delivery of intraocular pressure-lowering medication via topical instillation. But, this dosage form has practical limitations due to well-known ocular barriers to drug transport. For the first time, highly efficient compound eye drop formulation is designed based on the idea of innovative glutathione-functionalized gelling materials. Our biomaterials-based ophthalmic drops can better improve drug bioavailabilityantiglaucoma efficacy than currently marketed eye drops, thereby showing future clinical translational potential.

Gene delivery technology is widely used in cell therapy, nucleic acid-based vaccines, protein production, gene therapy, etc. We have developed a non-viral gene delivery technology-MPGene, which has excellent gene delivery efficiency (50-80) for human mesenchymal stem cells,also has the characteristics of low production costhigh safety. In the future, MPGene has the potential to be used in important biomedical fields such as gene delivery reagents, major trauma cell therapy, malignant tumor treatmentcartilage cell therapy.

A stem cell continuous harvest method was proposed. In this method, stem cells are partially detached. The remaining cells are continuously cultured by expansion in fresh culture medium.