"1. New method to prepare (3S, 3’S)astaxanthin, with high yield, high stabilityharmless to organism 2. The method has variety of biological activities anti-oxidation, anti-agingpromote damage tissue repair 3. It has anti-cancer potential, especially effective against metastatic cancer cells 4. Applied as Multifunctional medical supplies, functional foods, functional drinks, cosmeticsmaintenance products"

These stimuli-switchable nanoparticles coated with the cleavable outer polymer coatingmultifunctional peptides may afford a new platform for anticancer drugmiR. These nanoparticles possess characteristics of environmental response, active targeting,gene/chemo combinatorial therapeutics, thus providing spatiotemporal control of posttranｓｃｒｉｐｔional gene regulation, smart nuclear/mitochondrial localization,simultaneous inhibition of multiple progression pathways of tumor cells for enhancing antitumor efficacysafety of cancer therapy.

We developed Polypyrrole (PPy) based NIR-photothermal related platform technologies. This photothermal driving hyperthermia carrier systems are biocompatible are able to possess versatile functions in anticancer, antibacterial, thrombolysis, wound-healingsuppression of inflammation related bioengineering potential applications. These innovative works shed light on the efficacy of combining photothermal-performance with translational manner in biomedical, clinicalindustrial designs.

Effectively inducing cytotoxic T cell expansion has been a critical challenge in vaccine development. To address this challenge, an entirely biodegradable polymeric nanoshell was invented to couple antigensadjuvants for safepotent immune potentiation. The invention has been adopted for precision anticancer vaccine, broadly reactive influenza vaccine,an effective vaccine MERS-CoV.