We provide antibody-based solutions to human diseases with short development course at low cost, are based on the phage-displayed GH (Generic Human) synthetic antibody libraries designedconstructed with enabling approaches, leading to the throughput capacities to uplift the innovativenessproductivity in developing antibody therapeuticsdiagnostics. In conjunction with the core technologies, antibody bioinformatics capable of extracting knowledge from big data of human antibody repertoires is used to elucidate human antibody responsesto assist antibody library design.

The "Herbmedotcin" technology platform is a major breakthrough in the several thousand years history of herbal medicine knowledge. Use patented technology to find potential natural functional molecules, with appropriate additivesoptimal processing conditions, to achieve a significant increase in their efficacy. This technology is also known as "molecular herbology". They h

Our studies showed the endophyte Burkholderia 869T2 help banana to stand against the Panama diseaseimprove growths of pumpkin, cabbage,other crops. The 869T2 helps plants cope with salinity stresscan decrease dioxin accumulations in plants. The specific metabolite PQQ of 869T2 benefits host plant growths. The beneficial endophytethe metabolite can be developed as an protective endophytic agent.

The innovative microbial wastewater treatment technology of our team can effectively reduce the COD, BOD, total nitrogen and total phosphorus in livestock wastewater to the emission standards in a short period of time, and the generated microorganisms can be developed for feed additives and organic fertilizers. In terms of industrial wastewater, this technology can also effectively clean petrochemical, ammonia nitrogen and heavy metal wastewater by degrading COD and ammonia nitrogen even adsorbing heavy metals, showing the excellent treatment performances.

Chloroethene is carcinogenic which is extremely harmful to the human. Currently, the effect of bioremediation of chloroethene is efficientit is also friendly to the environment. However, dichloroethenevinyl chloride are the most products that will be accumulated in the environment after dechlorination. Our team isolate the first native Dehalococcoides in Taiwanalso develop a novel dechlorination bio-gel bioremediation technology with silica bio-gel column. Our immobilized system is ａ novel an efficient method to remediate chloroethene into ethene, a non-toxic compound.

By integration of professions including phytopathology, pesticides analysis, aquaticlivestock management, microbial fermentation, epidemiology,artificial intelligence, our interdisciplinary team jointly have developed microbial products for multi-industry applications including crop health care, circular agriculture, livestockaquaculture. The intelligent monitoring modelsmanagement technology for evaluating the efficacy of microbial products are implemented to provide key time pointdecision support for microbial products application,in turns to enhance the application efficacy. The developed microbial agentstechnology would greatly reduce the use of chemical pesticidesantibioticsenhance agricultural output valuemarket competitiveness.

In this research, we developed two platforms for analyzing mitochondrial stress. One is to use CRISPR/Cas9 editing to mark a variety of mitochondrial proteins in C. elegansmammalian cells for in vivo assessing mitochondrial functions. Another one is to establish a light-induced DNA damage specifically in mitochondria. In the meanwhile, we also developed a method to

X-ray diffraction technology is used to analyze the drug efflux pump, ST50, form S. Typhi. The drug efflux mechanism for multiple drug resistant (MDR) S. Typhithe potential location for antigen of market-based typhoid detection reagent are understood through this ST50 structure. It could help develop the more effective typhoid detection reagentthe new antibiotics against MDR S. Typhi.