We have developed the device recorded the neuronal action potential of multiple mouse brainstheir cerebellum with high sampling rate (30 kHz)multiple channels to accelerate the study of the pathogenesis of neurodegenerative diseases. The team hopes to extend the multi-channel BCI devicebrainwave technology to more neurodegenerative disease biomarker analysis to help pharmaceutical companies to explore the pathogenesis of neurodegenerative diseaseshelp in new drug developmentclinical diagnosis.

Constructing a functional connectome and its computational model is a crucial step toward understanding the mechanisms of brain functions. To achieve this goal, we developed two correlated technologies: (1) An all-optical physiology (AOP) that is capable of millisecond volumetric imaging and accurate stimulation in living animal brains. This system allows us to establish functional connectome and neural coding with a single-cell resolution. (2) A cellular-level spiking neural circuit simulation system that is capable of tuning itself based on the input data from the AOP system. We have demonstrated our technologies in the Drosophila late visual system and will apply them in the brains of larger species such as mice. Our technologies will greatly enhance knowledge of brain operation.