An innovative ointment solves an unmet clinical need to cure keloid wounds The composition of the ointment can precisely modulate the cell functionsgene expression of keloid fibroblasts, making them close to the performance of normal fibroblasts. Thereby, when applying the ointment to keloid woundsthe human body prone to the formation of keloid wounds, the wound is smoothed, healing close to normal skin.

Chronic wound infection is a leading cause of mortality in injured patients worldwide. At present, available systemic antibiotic treatments have an insufficient tissue penetration ability and allow the development of antibiotic-resistant pathogens. The identification of therapeutic agents with wound healing and antimicrobial functions is necessary to heal the wound and cure infections. Our report shows that the antimicrobial peptide (AMP) Epinecidin-1 (Epi-1) efficiently heals MRSA-infected heat burn injuries and provides protection from infection in mouse and pig model. Our results demonstrate that the biomaterial Epi-1 heals wounds through increasing epithelial cell proliferation, vascularization, and the formation of collagen and controls MRSA infection-mediated sepsis in pigs.