Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.

Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.

1. ‘Mobile Application for Anti-Doping’ containing more than 40,000 pharmaceuticals which allows athletes to check whether the pharmaceuticals are prohibited in-out-of-competition simply via typing in the product names. 2. ‘Gastroenteritis Defender’ utilizes nanotechnology to enhance andrographolide oral bioavailabilitycould effectively prevent gastrointestinal inflammatory disorders.

The bioactive corecorona synergism of sub-nanometer gold enables slowed inflammationincreased tissue regeneration in wound hypoxia. The developed dual-function wound dressing based on a gold nanocluster with a plane structurean adhesive layer presented two features: (1) the gold nanocluster can attenuate the inflammatory response by adjusting the strength of the active site (i.e., l

This technology is mainly solved the side effects of anti-obesity drug, including soft stoolsoily stools,regulate oil absorptionmetabolism as an additive in food. During the experiment, the curing phenomenon of MSNs/oiloily stool reduction in animal were observed. In conclusion, MSNs can effectively reduce the side effects of Orlistatelevating life quality.

The time-temperature indicator (TTI) developed by immobilizing laccase on electrospun fiber film with high specific surface area. The activation energycoloration of laccase TTI can be adjusted by pHaddition level of laccaseNaN3. This TTI exhibits high accuracy, stability, temperature reversibilitylow cost. The intelligent food packaging developed by this TTI can reduce the food wastethe food safety risk in traditional packaged foods.

"The designed ultrasound gel is modified with nanocrystalnanofiber. The product is designed to be sterilizablefits well to the ultrasound probe. With such nanomaterials, our product shows great ultrasound transmission abilityenhanced mechanical strength. The highlights of the this ultrasound agent include: (1) Enhanced compressibilitytensile strength with adjustable composition. (2) Improved infection controlreduced risk of complication. (3) Improved transmission depth with certain thicknessimproved image quality within superficial region."

Gene delivery technology is widely used in cell therapy, nucleic acid-based vaccines, protein production, gene therapy, etc. We have developed a non-viral gene delivery technology-MPGene, which has excellent gene delivery efficiency (50-80) for human mesenchymal stem cells,also has the characteristics of low production costhigh safety. In the future, MPGene has the potential to be used in important biomedical fields such as gene delivery reagents, major trauma cell therapy, malignant tumor treatmentcartilage cell therapy.

Here we present a portable microfluidic device that can perform immunoassay for infectious disease diagnosis or detect heavy metal ions in water samples. The device is composed of two major components: nanomaterials modified paper-based detection platform and semi-automated flow manipulator. A reusable 3D-printed device is used to hold a disposable detection pad that modified with functional nanomaterials for water quality monitoring or antibodies for disease diagnosis. Besides, the use of spring-containing 3D-printed syringes manipulates a large-volume sample without manual actuation. Meanwhile, by controlling the flow rate via the linked flow regulator at the syringe outlet, solutions can react stably with the paper platform, which provides detection and pre-concentration effects.

The present invention relates to a solid sodium carbon dioxide battery, which can utilize carbon dioxide gascan chargedischarge at room temperature. This solid carbon dioxide battery is composed of a positive electrode, a negative electrode,an inorganic solid electrolyte sheet. In order to improve the contact between the electrodethe inorganic solid electrolyte sheet, a positive/negative interface layer can also be introduced.

Devices with physical flexibilitystretchability have attracted a great deal of interest for use in wearable electronic technologylarge-area electronics, including displays, energy harvesters, energy storage devices, distributed sensor networks,Internet of Things applications. The present invention relates to methods for growingtransferring single-crystal III-nitride nanorodstwo dimensional transition metal dichalcogenides (2D TMDs) nanostructures,devices having the transferred nanostructures for flexible device, microLED,3DIC fabrications.

"Establish an immunological-based platform for nano drug: 1. Establish macrophages as an in vitro cell-based testing platform 2. Safety assessmentimmunomodulatory effects of nano drugs 3. Gold nanodots as a specific target of Nrf2 pathway against chronic diseases."

Effectively inducing cytotoxic T cell expansion has been a critical challenge in vaccine development. To address this challenge, an entirely biodegradable polymeric nanoshell was invented to couple antigensadjuvants for safepotent immune potentiation. The invention has been adopted for precision anticancer vaccine, broadly reactive influenza vaccine,an effective vaccine MERS-CoV.

Supramolecular nanoparticles is a convenient, flexible,modular synthetic non-viral gene delivery vehicle for drug/gene delivery. The self-assembly of SMNPs is enabled upon mixing three different molecular building blocks, namely CD-PEI, Ad-PAMAM,Ad-PEG via Ad/CD motif-based molecular recognition. This allows modular control over the sizes, surface chemistry,payloads of SMNP vectors, thus holding promise for diverse therapeutic applications, especially for developing nanoparticle-based gene delivery platforms.

Energy-saving glass is realized using nano-imprinting to fabricate a periodic nano-structures. The glass can suppress the transmission of ultraviolet light such that people are not harmed. The transmission of infrared is largely reduced to lower air-conditioning. On the other hand, transmission is not deteriorated in the visible range to prevent the increment of illumination cost.

Nanopharmaterial is a term by combining pharmaceuticalmaterial via nanotechnology. Here we demonstrate this concept by developing a novel nanopharmaterial, so called 177Lu-Gold nanostar (AuNS). 177Lu is a therapeutic radionuclide emitting moderate-energy beta particles as well as gamma rays for SPECT/CT-based imaging diagnosis. Nanostar can target tumors by enhanced permeability retention (EPR) effectsowns the photothermal therapeutic potent. The core technology is to integrate radionuclidenanomaterial to perform a new radio-nanopharmaterial for tumor target theranostic purpose.

A portablemagnetic surface Raman-enhanced scattering (SERS) nanoparticle arrays platform would be developed for magnetic separationSERS detection of environmental, water,biomolecules samples. It is very simplerapid platform with portable Raman spectroscopy to detect samples (bacteria, virous, water toxicants) after magnetic separation processes, without labelling the fluorescence dye,the limit of detection concentration is lower than 10-8 M.

The chromium-doped zinc gallate, ZnGa2O4:Cr3+, material is viewed as a long-lasting luminescent phosphor which can avoid tissue autofluorescence interference for in vivo imaging detection. The cubic ZGC revealed a specific accumulation in liver0.5 Gy used at the end of X-ray excitation was sufficient for imaging of deep seated hepatic tumors.

Materials for power device packaging should endure high temperature, high voltage,high current density to handle various harsh working conditions. We developed Cu NP pasteCu/Sn paste for low temperature bonding technique. No toxic chemicals are present in the synthesis processin the pastes. The pastes can bond Cu substrates at low temperature without applying pressure. The joints possess high melting temperature, high thermal stabilityexcellent mechanical properties.

The objective of this study is to develop a high energetic ignition powder which combines the features of nano-aluminum (nAl) powderNitrocellulose (NC)Ammonium perchlorate (AP). The study covers from the deployment of the igniter using above three materials, the research of the ignition mechanismthe application in engineering field.

Nano-sized silicon reacts rapidly with most water solutions to form pure hydrogen. However, high costlow availability are major issue. Our group has developed novel nano-sized silicon mass-production process, greatly improves its feasibilitycost for hydrogen generation. The in-time hydrogen generation by nano-size silicon, fuel-cell systemlithium ion battery system are all well integrated into one portable power system, which can satisfy general personnel electricity demand for some special conditions, such as battle field, emergency caseremote regions.

This technology＇s nanofluid/ultrasonic atomization micro-lubrication system is different from the general micro-lubrication technology that uses high-pressure air atomization. It is first to use cavitation characteristics to disperse a small amount of nanofluid into microscopic particleseffectively disperse the bondingagglomeration of nanoparticles due to the Van der Waals force. The second stage of atomization is carried out through high-pressure air. The oil mist particles of the nanofluid can easily enter the micro-machining cutting area for coolinglubrication.

We developed a chicken mucosa-targeting polymeric nanoparticle vaccine (~90 nm) co-delivering viral antigenCpG adjuvant using a water-in-oil-in-water double emulsion technique. The particles are biodegradablebiocompatible. This nanoparticle significantly stimulated chicken Harderian gland B cell proliferationsubsequent local IgAIgG secretion in tears. The mucosal Ig protected chickens from virus infection by lowering virus replication at the infection sitethereafter reducing tracheal epithelial ciliostasissystemic infection, relieving clinical symptoms.

Our research team has developed a short-wave infrared light gold nanoclusters as an intraoperative fluorescent imaging agent, breaking the light emission limit of the previous gold nanoclusters, shifting the light emission position to the infrared spectrum, successfully avoiding the autofluorescence between the tissuesachieve deeper penetration along with instant bio-imaging. This technology has clearerdeeper imaging benefit with the potential to become a clinical medical infrared imaging agent.

PCR, a gold-standard diagnostic method, were labor-intensive, time-consuming,costly, which restricted its application to widespread screening. Herein, this study purposes a one-potnon-washing method to rapidly detect virus by dual-SERS mechanism. COVID Antigens were captured by SERS nanoparticlesnovel SERS substrate simultaneously to achieve 6 order enhancements within 20 minutes. The dual-SERS sensors have reached a detection limit of 1 ng/ml in clinical samples for recognizing nucleocapsid & Spike proteins of COVID-19, which is comparable with PCR results.

In CB-XLCT imaging, when nanophosphors are delivered to tumor tissues,irradiated by X-rays, luminescent light with wavelength range of 500-700 nm will be exciteddetected by optical camera from different directions. After reconstruction, it can provide tumor locations. The micro-CT subsystem also provide X-rays to excite nanoparticles for luminescence tomography.

Biomimetic adhesive has some characteristics: no residual glue, anisotropic adhesion, easy to be peeledstuckrepeated. Its adhesion could be adjusted depend on the application. The adhesive can be applied but not limited in wafer processing, movement of optoelectronic materials, 3C product assembly, daily-used fixation,producing a protective film for attaching to an object surface.

With the development of photonics, there has been a push towards optoelectronic devices that are flexible, rollable, wearable, user-friendly, and robust to improve human-machine interfaces. To be integrated onto human body, these devices must be biocompatible and be able to withstand mechanical deformation and different bending curvatures. Figure 1 shows the rollable and soft photonic meta-device.

Integrated Taiwan＇s superior industries such as semiconductor manufacturing processes, precision micro-molding, hot embossing,chip packaging to develop Pt/Au nano-alloy electrodes with applications in neutral non-enzymatic glucose biosensorsneutral non-enzymatic glucose biofuel cell. This novel Pt/Au nano-alloy electrode possesses advantages of technology foresight, good detection perfor

1. A novel three-dimensional skin equivalent 2. A supercritical extraction system preserves bioactivity: no toxicity, environmental friendly, high efficiency, refine efficient biological elements 3. Advantages of hydrogel: large area ‎30 s quick-drying coolpain-killing transparentdifficult to observe moisturization tensioncontraction biodegradation easy to clean / makeup