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These stimuli-switchable nanoparticles coated with the cleavable outer polymer coatingmultifunctional peptides may afford a new platform for anticancer drugmiR. These nanoparticles possess characteristics of environmental response, active targeting,gene/chemo combinatorial therapeutics, thus providing spatiotemporal control of posttranｓｃｒｉｐｔional gene regulation, smart nuclear/mitochondrial localization,simultaneous inhibition of multiple progression pathways of tumor cells for enhancing antitumor efficacysafety of cancer therapy.

Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.

Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.

Nano-sized silicon reacts rapidly with most water solutions to form pure hydrogen. However, high costlow availability are major issue. Our group has developed novel nano-sized silicon mass-production process, greatly improves its feasibilitycost for hydrogen generation. The in-time hydrogen generation by nano-size silicon, fuel-cell systemlithium ion battery system are all well integrated into one portable power system, which can satisfy general personnel electricity demand for some special conditions, such as battle field, emergency caseremote regions.

Develop a SiC single-chip power system platform across processes, devices,circuits to breakthrough the temperaturepower constraints of Si applications. The research includes low-voltage CMOS logic circuits, high-voltage driver circuits,vertical super-junction MOSFETs. All specifications exceed existing technology. The results can be applied to energy networks, rail transit, new energy vehicles, geological exploration, aerospace, defenseother fields.

A novel 3D-stack LTPO-based display array technology with CBRAM-embedded in a pixel has been successfully developed for the high-resolutionpower-saving near-eye VR/AR displays. Besides, a high-voltage gain CMOS inverter comprised by LTPO architecture is demonstrated acting as a digital driving circuit for the realistic FPD applications.

This 1.6Tb/s silicon photonic chip adopts the semiconductor technology to integrated optical couplers, splitters, modulators, and 4x16 AWG optical multiplexer into a 5mm x 5mm area. Thanks to the support of Ministry of Science and Technology (MOST) and Taiwan Semiconductor Research Institute (TSRI), this novel 1.6Tb/s silicon photonics chip is designed at the end of 2018 and send to IMEC to produce. After getting the chip at the beginning of 2020, those separate devices of optical edge coupler, optical splitter, optical modulator, and 4x16 AWG optical multiplexer have been measured and verified. The overall chip performance has also been checked by injecting lasers and the light signal has been coupled by singlemode fiber to demonstrate the feasibility of this novel silicon photonics chip.

The location of controlled-grain Si island is determined by the pattern of “cooling holes”. The grain size is determined by the distance between “holes” due to lateral grain growth using pulse laser crystallization. This predictability allows the transistorscircuits to stay away from the grain boundaries for monolithic

Our technology uses GaN (gallium nitride)SiC (silicon carbide) wide band gap semiconductor materials to develop high radiation hardness semiconductor technologies for space applications. GaNSiC-based materials feature with a strong bondingsmall lattice constant. Furthermore, the displacement energy of GaNSiC-based materials is greater than 10 times that of silicon. Therefore, GaNSiC-based device can exhibit a better radiation hardness than the Si-based devices, indicating that GaNSiC-based electronics are promising for the space applications.

The research topics include advanced power supply, energy storage techniques, electromechanical integration, electric vehicles,power system control. Based on the existing researchdevelopment foundation, focusing on energy conversion efficiency, high-voltage charging (fast charging), device miniaturizationlight weight, smart power management solutions, etc., with lightweight materials. Develop a power management solution to instantly monitor the power statuscharging device. The application of management to achieve the vision of a smart city.

The microfluidic chips have been used to sort human motile sperms based on the phenomena of laminar flow. The sorted sperms would be fertilized to form the embryo by using in intracytoplasmic sperm injection (ICSI). The prototype of chips have been developed in the lab under National Tsing Hua University. Furthermore, the mass production has been conducted by Ritek to accomplish the disposable chips

This technology is mainly solved the side effects of anti-obesity drug, including soft stoolsoily stools,regulate oil absorptionmetabolism as an additive in food. During the experiment, the curing phenomenon of MSNs/oiloily stool reduction in animal were observed. In conclusion, MSNs can effectively reduce the side effects of Orlistatelevating life quality.

This project with aim of promoting digital optics education is funded by Ministry of Education. In the entry-level class, students are guided in the hand-on experiments to bring up the ability to set up optical pathsto learn the basic optics principles. In the advance-level class, students are encouraged to work on a 3D holographic project using the fast-response LCOS-SLM developed in Digital Optics Teaching Laboratory of NYCU. Students are able to apply different computer-generated holography (CGH) algorithmsdesign optical path accordingly to obtain desired holographic images.

In the prior art of high-efficiency anode materials for lithium-ion batteries, we designed a high-entropy compositionmanufactured it through a simplemass production method. This technology inherits the cocktail effect of high-entropy alloys by combining highly active elementsmetal elements. This material can be manufactured by a simple mass production method. It shows high energy density, high Coulomb efficiencyhigh cycle stability,becomes a promising anode material for lithium-ion batteries.

The aim of this study was to develop of high safety, high performance sulfide-based all-solid-state Li-ion battery (ASSLIB). The ASSLIB composes of a flexible, high ionic conductive,moisture insensitive sulfide-based solid-state electrolyte (SSE) film, Si/C composite anode material with self-healing polymer binder, high capacity LiNi0.8Co0.1Mn0.1O2 (NMC811) composite cathode,garnet-in-polymer solid composite interlayer to prevent decomposition of sulfide-based SSE with electrode materials.