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These stimuli-switchable nanoparticles coated with the cleavable outer polymer coatingmultifunctional peptides may afford a new platform for anticancer drugmiR. These nanoparticles possess characteristics of environmental response, active targeting,gene/chemo combinatorial therapeutics, thus providing spatiotemporal control of posttranｓｃｒｉｐｔional gene regulation, smart nuclear/mitochondrial localization,simultaneous inhibition of multiple progression pathways of tumor cells for enhancing antitumor efficacysafety of cancer therapy.

Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.

Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.

This 1.6Tb/s silicon photonic chip adopts the semiconductor technology to integrated optical couplers, splitters, modulators, and 4x16 AWG optical multiplexer into a 5mm x 5mm area. Thanks to the support of Ministry of Science and Technology (MOST) and Taiwan Semiconductor Research Institute (TSRI), this novel 1.6Tb/s silicon photonics chip is designed at the end of 2018 and send to IMEC to produce. After getting the chip at the beginning of 2020, those separate devices of optical edge coupler, optical splitter, optical modulator, and 4x16 AWG optical multiplexer have been measured and verified. The overall chip performance has also been checked by injecting lasers and the light signal has been coupled by singlemode fiber to demonstrate the feasibility of this novel silicon photonics chip.