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These stimuli-switchable nanoparticles coated with the cleavable outer polymer coatingmultifunctional peptides may afford a new platform for anticancer drugmiR. These nanoparticles possess characteristics of environmental response, active targeting,gene/chemo combinatorial therapeutics, thus providing spatiotemporal control of posttranｓｃｒｉｐｔional gene regulation, smart nuclear/mitochondrial localization,simultaneous inhibition of multiple progression pathways of tumor cells for enhancing antitumor efficacysafety of cancer therapy.

Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.

Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.

Our present invention firstly provides a new ultrasound (US)-multifunctional microbubble (MB) which can be applied to a topical region of the body surface of organisms by applyingsputtering, instead of using injection. Some interesting topics have been explored: 1. US-aided MBs facilitate the delivery of drugs to the inner ear via the transcanal method, 2. drug-carrying modified MB combine wit

1. A novel three-dimensional skin equivalent 2. A supercritical extraction system preserves bioactivity: no toxicity, environmental friendly, high efficiency, refine efficient biological elements 3. Advantages of hydrogel: large area ‎30 s quick-drying coolpain-killing transparentdifficult to observe moisturization tensioncontraction biodegradation easy to clean / makeup

Our core generated several types of transgenic micea stable humanized ACE2 mice using a combi-CRISPR genetic engineering technique. We hope these mouse models can help to dissect COVID-19 pathogenic mechanismthe interaction(s) between spike proteinACE2 K353.

Innovative wearable monitoring device for pregnant women can record the signals of contractions, fetal movement,fetal heart rate in real time. With AI intelligent classificationsequential analysis technology, it can link the difficult-to-classify GTC signal patterns with the possibility of fetal distress Finally, the position, sizeduration of fetal movement are further estimated to provide accurate follow-up clinical analysis. It allows pregnant women to monitor the relevant physiological parameters at any time at home to avoid the troublesworries caused by the risk of nosocomial infection of pregnant women.

Compared with the isolation areathe outdoor environment, the air pressure isolation channel is a positive pressure environment. It can completely avoid that the unsterilizedfiltered air outside the building will not enter the isolation area,perform regional protection to maintain the cleanliness of the indoor environment.

SeraParma™ COVID-19 IgM rapid test has high detection sensitivity, which can provide rapid detection of early COVID-19 infection. This SeraParma™ COVID-19 IgM rapid test can detect whether there are IgM antibodies produced in the early stage of infection (within 7 days of symptoms onset) with one drop of the specimen (serumfingertip blood) in 15 minutes by naked eyes compared with LFIA antibody rapid test. It is worth noting that the SeraParma™ COVID-19 IgM rapid test can accurately detect the patients with positive infection within 7 days of the onset of symptoms compared with LFIA.

1. Identification of host factor, which is required for virus replication, by “EditCell Virology Platform”. 2. The host factor will be as a target to develop antivirals. 3. The antiviral effects of the candidates can be validated in vitro and in vivo. 4. Two FDA-approved drugs are repurposed for COVID-19 treatment.