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Precision Health Ecosystem FutureTech A platform for combinatorial therapy of genechemotherapeutics: nanoparticles with pH-detachable coatingtargeting peptides for specific delivery to the nucleusmitochondrion of multiple
These stimuli-switchable nanoparticles coated with the cleavable outer polymer coatingmultifunctional peptides may afford a new platform for anticancer drugmiR. These nanoparticles possess characteristics of environmental response, active targeting,gene/chemo combinatorial therapeutics, thus providing spatiotemporal control of posttranｓｃｒｉｐｔional gene regulation, smart nuclear/mitochondrial localization,simultaneous inhibition of multiple progression pathways of tumor cells for enhancing antitumor efficacysafety of cancer therapy.
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Smart machinerynovel materials FutureTech Application of inorganic nanofiber technology to promote the development of biotechnology
Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.
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Smart machinerynovel materials FutureTech (test)Application of inorganic nanofiber technology to promote the development of biotechnology
Inorganic porous nanofibers with surfaceinterface defects are prepared through humidity-controlled electrospinninghigh-temperature annealing technology. Under the irradiation of light sources of different wavelengths (380~780 nm), the bound electrons stored in the valence band can be excited to the conduction band to form free electrons on the surface of the material, generating different intensities of microcurrents, light sensitivitymicrocurrent changes. Because the "inorganic nanofiber" technology has high uniquenesshigh product compatibility, it can be applied to a wide range of markets.
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Medical Devices FutureTech Microfluidic motile sperm separation sorter
The microfluidic chips have been used to sort human motile sperms based on the phenomena of laminar flow. The sorted sperms would be fertilized to form the embryo by using in intracytoplasmic sperm injection (ICSI). The prototype of chips have been developed in the lab under National Tsing Hua University. Furthermore, the mass production has been conducted by Ritek to accomplish the disposable chips
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