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Precision Health Ecosystem FutureTech 多模肺癌臨床智慧決策分享輔助系統
The proposed technologies apply deep learning methodsbig clinical data for lung cancer decision support. The system consists of: 1) CT radiogenomicspatho-genomics for automatic cancer detectionprediction of EGFR mutation 2) demographics to predict survival 3) genomics to predict cancer recurrencemetastasis,4) drug response inference for the best target therapy option. The modules are constructed on an AI-based Clinical Decision Support System (CDSS-SDM). The system is expected to provide physicianspatients with personalized medication recommendations.
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Precision Health Ecosystem FutureTech 應用於血栓溶解治療之創新超音波漩渦技術
We have developed an innovative acoustic vortex technology VorteSonic for treatment of VTE, with the first go-to-market product of a catheter-based acoustic vortex thrombolytic device. Acoustic vortex produces turbulent flow around the thrombus, resulting in effective thrombolysis by creating loose structure of thrombustherefore enhancing deep penetration of thrombolytic drugs into the thrombus. Advantages of the acoustic vortex technology is reduction of hemorrhagic riskimprovement of safetyprognosis. Feedback system can be integrated for intelligent therapy in the future.
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Precision Health Ecosystem FutureTech A platform for combinatorial therapy of genechemotherapeutics: nanoparticles with pH-detachable coatingtargeting peptides for specific delivery to the nucleusmitochondrion of multiple
These stimuli-switchable nanoparticles coated with the cleavable outer polymer coatingmultifunctional peptides may afford a new platform for anticancer drugmiR. These nanoparticles possess characteristics of environmental response, active targeting,gene/chemo combinatorial therapeutics, thus providing spatiotemporal control of posttranｓｃｒｉｐｔional gene regulation, smart nuclear/mitochondrial localization,simultaneous inhibition of multiple progression pathways of tumor cells for enhancing antitumor efficacysafety of cancer therapy.
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