Technical Name Nebulum3D Bioimaging System
Project Operator National Tsing-Hua University
Project Host 江安世
Summary
Nebulum 3D Bioimaging combines Tissue Clearing, Light-Sheet Microscopy, and Tissue Expansion, to provide a streamlined bio-imaging service that bypasses the conventional sectioning technique and provides whole-tissue, multiplex, single-cell resolution imaging data.
Scientific Breakthrough
We are the first in the world to observe a memory protein's formation on a single neuron with specific 3D coordinates at single-protein resolution using Nebulum3D in a drosophila brain. We also found that other types of memory protein will accumulate on the same neuron during new memory formation.
Industrial Applicability
Nebulum3D is the next generation tool for tissue morphology and pathology analysis. This technology can be applied to brain structural and related drug development projects, high-speed cancer drug screening and analysis, and pathological detection and diagnosis.
Keyword Multiscale Light-Sheet Imaging Super-Resolution Imaging Whole-Tissue Imaging Tissue Clearing Tissue Expansion 3D Drug Screening 3D Pathology Bioimaging Alzheimer's Memory
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