Technical Name | Engineeredclonally selected cell lines for higher virus titer | ||
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Project Operator | Research Center for Animal Biologics, National Pingtung University of ScienceTechnology | ||
Project Host | 邱明堂 | ||
Summary | Our platforms include:1.Cell/Virus clone selection, 2.Expression of virus receptors in cells,3.Blocking cells’ antiviral response, 4.Immortalization of primary cells,5.Serum-free suspension cell culture. This can enhance virus titers, vaccine production efficiency, developing new vaccines,up to industrial scale with vaccine qualitylower costs. |
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Scientific Breakthrough | By using this technique platform we can improve virus titeralso improve efficiency of vaccine production for 10 to 10000 fords in comparison to current industrial techniques.(Table 2) |
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Industrial Applicability | This technology was used to develop varieties of animal vaccines as the table 4. |
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Keyword | Cell Virus Antigen Vaccine Bioreactor Cell culture Virus mass production Interferon Suspension culture Gene editing |