Technical Name |
Polysorbasome |
Project Operator |
National Health Research Institutes |
Project Host |
黃明熙 |
Summary |
Polysorbasome (PSS, polymeric absorbable vehicle) is a colloidal vehicle made from polymeric bioresorbable amphiphiles (PEGylated polyesters/sorbitan polyesters). Structural features allow the vesicles to act as an immunogenic depot for sustained delivery of vaccine antigensto be absorbed post-vaccination, suggesting new insights into innovative vaccine design. |
Scientific Breakthrough |
"Novel polysorbasomes have versatile advantages over common vaccine formulations, as follows:
Soft for easy injection.
Safe for massive vaccination.
Small for cell recognition.
Smart for antigen immunoavailability.
Simple for reducing cost.
Stimulatory for eliciting appropriate immunity."
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Industrial Applicability |
Fields of applicationmarket potential are biodegradable controlled-release vaccinedrug delivery systems, immunotherapy for chronic diseases such as cancer, autoimmuneallergy,mucosal delivery.
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Keyword |
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