The International Center for Wound RepairRegeneration of National Cheng Kung University transferredestablished Ducolege Biotechnology Co., Ltd., using Extre2Cold exclusive extraction technology to extract highly active marine collagen from Tilapia fish skin, which is type I collagen with a complete molecular structurehas a three-stranded helix structure. It is biologically activeperfectly presents the magical ability of fish skin to repair wounds. It can be widely used in biomedical materialsacademic research. It is currently first promoted in the development of high-level medical beauty repairmaintenance products, which is helpful for repairing damaged skin.

Epidermolysis bullosa (EB) is an inherited blistering skin diseaseis also one of the most "urgent, severe, difficultrare" diseases. Since there are at least 21 disease-causing genes involved in EB with markedly variable manifestations, it is particularly difficult for accurate diagnosis. In recent years, next generation sequencing (NGS) has been widely applied in the genetic diagnosis of rare hereditary disorders. The EB team in NCKU established the protocol of EB diagnosis by combining NGSvarious tools of pathologymolecular studies. Till now, we have completed the genetic diagnosis for more than 50 Taiwanese EB patients.