Cancer is the first leading cause of death in Taiwan. Targeted therapy allows the cancer cells to be specifically targeted, reduces the side effects,achieves the purpose of precision cancer treatment. This report contains two invention technologies which combined early & specific diagnosis of a specific Aurora-A mRNA isoform in cancers (the companion diagnosis)the treated with a selective locked nucleic acid (LNA)-modified novel double-stranded short interfering nucleic acid (siRNA) to inhibit the translation of this Aurora-A mRNA isoform (targeted therapy) in cancers.

This rapid diagnostic device for monitoring the abnormal growth of the endometrial tissue is expected to allow women to detect whether VEGFIL-6 are too high at home in a simplerapid manner. These two factors are also increasing in some gynecological cancers. Through the new device, it is convenient for women to self-monitoring women physiologically-relevant diseasespossible causes of abnormal bleeding in the future,seek appropriate medical treatment early.

The red-leaf aglaonema were promoted growth of by water-retaining materials. For the growers, the technology can effectively shorten the duration of cultivationpromote the quality of potted flower. Therefore, the technology solves the problems of productionwill have practical application in the industry.

Our studies showed the endophyte Burkholderia 869T2 help banana to stand against the Panama diseaseimprove growths of pumpkin, cabbage,other crops. The 869T2 helps plants cope with salinity stresscan decrease dioxin accumulations in plants. The specific metabolite PQQ of 869T2 benefits host plant growths. The beneficial endophytethe metabolite can be developed as an protective endophytic agent.