This project designs a biomedical theranostic chip for neural disorders. It can not only function as an implantable device for treating the Parkinson＇s disease, depression, dementia, but also monitor physiological signals in wearable devices. For the development of medical device, the NeuLive system based on the microchip can accelerate the pre-clinical data collectionverification.

A method of enhancing a mammalian immune response to a virus is disclosed. The method comprises administering a composition comprising an effective amount of epinecidin (Epi)-1the virus to a mammal, wherein the virus has envelope proteinis infectious to the mammal. In this technique, Epi-1Japanese encephalitis virus (JEV) were mixedinjected into mice. The mice were infected with JEV 14 days later,all mice survived. This technology has also been verified in the preparation of vaccines for foot-and-mouth disease virusnervous necrosis virus.

Our core generated several types of transgenic micea stable humanized ACE2 mice using a combi-CRISPR genetic engineering technique. We hope these mouse models can help to dissect COVID-19 pathogenic mechanismthe interaction(s) between spike proteinACE2 K353.

Our team has developed technology to build lung-on-a-chip with the aim of creating alternatives for animal researchachieving more accuratereliable preclinical experimental data.The chip＇s rapideffective screening ability will help the clinical community to reduce costsdrastically shorten the drug-development process.

The Center has established a high biological conservation center for the breeding of P. monodon shrimp seeds that meet international standards,has integrated more than 40 professional technologies to select P. monodon shrimp strains that are specific pathogens free (SPF)have special traits for stocking in the three-hectare commercial P. monodon shrimp seed expansion test site in Hualien. This will provide a stable supply of good P. monodon shrimp seeds for use by the Taiwan aquaculture industry.

This project is to implement a 37-40 GHz mmWave transceiver supporting 4096 QAM modulationis utilized for long-distance 4K/8K real-time image data transmission. The 37-40GHz band is divided into 500 channels,the AI technology is used for the TRx to carry out digital calibration. The achievement is TRx module (SoC/SiP)would be installed on the UAV for wildlife resources monitoring.