Technical Name Engineering DNA nano-computing devices to trackmonitor the progression of complex diseases
Project Operator National Yang Ming Chiao Tung University
Project Host 陳瀅州
Summary
Our team has developed "YouSync" (Yeast Homologous Synthetic Counter), a groundbreaking technology utilizing CRISPR/Casyeast mating-type switching for computationstorage in living cells. The crux of YouSync's innovative design is its binary computing system utilizes the binary numerals "0""1" to conduct operations. This transforms cells into sophisticated tools for logic operationsmemory storage, enhancing precision in cell detectiondisease monitoring.
Scientific Breakthrough
YouSync harnesses DNA nano-computing to turn cells into micro-biological computers for logic operationsdata storage. It surpasses existing technologies with unmatched sequential, time-dependent memory operations. Its capacity for early disease detectiondisease progression tracking surpasses any other technology, accelerating the detection of neurodegenerative diseases. YouSync fuels progress in biomedicine, drug development,public health.
Industrial Applicability
YouSync is an innovative binary cellular counter within synthetic biological recorderslogic circuits. Utilizing homologous recombination of DNA, this system equips cells with new functions to senserecord complex environmental information by converting genetic ATGC to editablerecordable binary codes. This technology promises widespread applicability in medical research, offering customizable genetic module kits for early disease detectiondisease progression tracking.
Keyword Biocomputer Synthetic biology CRISPR/Cas Binary Precision medicine
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  • Ying-Chou Chen
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