Our solution is able to noninvasively reconstruct 3D skin microstructuremicroangiography with micrometer-scale resolutions for diagnoses of skin disorders. Moreover, various skin parameters can be quantitatively evaluated from 3D images according to the proposed algorithms, including the thickness of stratum corneum, the thickness of epidermis, water concentration, collagen concentration,skin roughness. The developed technique can be applied to different clinical environments including hospitalscosmetic clinics for diagnosesanalyses of skin.

In this study, we develop a portable, high-imaging-speed, multi-functional 3D skin scanner which is based on the OCT technique. This 3D skin scanner is composed of four components including a miniaturized SLD light source, a miniaturized scanning probe, a high-speed spectrometer,a miniaturized fiber interferometer. Aside from acquisition of skin microstructuremicroangiography, the software algorithms are also developed for estimating skin conditions, including the algorithms for skin segmentation, angiography, water concentration, drug delivery,vessel density. After estimation from 3D imaging dataset, the skin parameters can be acquired. It will take 5-10 seconds to acquire a 3D datasetthe 3D images can be shown in real time.

We develop a portable, high-imaging-speed, multi-functional 3D skin scanner which is based on the OCT technique. With the developed system, 3D microstructuremicroangiography can be obtained simultaneously. Moreover, various skin parameters can be quantitatively evaluated from 3D images according to the proposed algorithms, including the thickness of stratum corneum, the thickness of epidermis, water concentration, collagen concentration, skin roughness,so on. According to the abovementioned functionality, the developed technique can be applied  for diagnosesanalyses of skin.

天使投資人、策略合作夥伴