| Technical Name | Engineered and clonally selected cell lines for higher virus titer | ||
|---|---|---|---|
| Project Operator | Research Center for Animal Biologics, National Pingtung University of Science and Technology | ||
| Project Host | 邱明堂 | ||
| Summary | Our platforms include:1.Cell/Virus clone selection, 2.Expression of virus receptors in cells,3.Blocking cells’ antiviral response, 4.Immortalization of primary cells, and 5.Serum-free suspension cell culture. This can enhance virus titers, vaccine production efficiency, developing new vaccines, and up to industrial scale with vaccine quality and lower costs. |
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| Scientific Breakthrough | By using this technique platform we can improve virus titer and also improve efficiency of vaccine production for 10 to 10000 fords in comparison to current industrial techniques.(Table 2) |
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| Industrial Applicability | This technology was used to develop varieties of animal vaccines as the table 4. |
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| Keyword | Cell Virus Antigen Vaccine Bioreactor Cell culture Virus mass production Interferon Suspension culture Gene editing | ||
- kegm@mail.npust.edu.tw
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