This novel process can fabricate a three-dimensional and visualized vessel model with hollow structure and flexible wall thickness. A 3D printer was used to create the molds, followed by solvent polishing. Then, the PDMS material is poured into the mold cavity for casting. Once the PDMS is released from mold inserts, the inner mold is dissolved with solvent, thereby obtaining an aneurysm model.

Experiments from this three-dimensional and visualized model can be used to validate numerical simulations, and to study the influence of the blood vessel geometry to the formation of aneurysm. Besides, this model can be used for training intern doctors of how to conduct the intracranial aneurysm surgery, which will improve the training quality as well as to lower the failure rate of surgery.

Model reported herein can be customized with benefits of: (1) This model is established from the medical image of specific patient, so the doctor can use it to explain the surgical procedure and the operation; (2) this model can be used as a teaching tool for interns; (3) the results from this model can be used to validate the simulation results and improve the level of related research fields.