Breath analysis has received among kinds of volatile organic compounds (VOCs), because of its potential as a non-invasive method for disease diagnosis and metabolic status monitoring. This technology is combined between the nanomaterials and micro-heater system of micro-electro-mechanical systems (MEMS) application of portable type device and then uses the bluetooth function to feedback the detection concentration to the smartphone, which helps diabetic patients as a home monitoring self-metabolic function.

The gas sensor has the function of monitoring abnormal fuctionanl metabolis. This non-invasive home detection instrument can avoid the pain of traditional needle sticks. Moreover, the device is simple operation and rapid detection. Portable sensor makes home care much convenient, because non-intrusive detection is not common in recent commercial sensors. Also, the MEMS manufacturing technology can miniaturize the dimension of sensing devices, and thus,  it is much suitable for the application of consumer electronic products.

This non-invasive detection method can more conveniently monitor the diabetic patients metabolic status, because the ketone gas is a biological symbol for the breathing of diabetic patients. In addition, used micro-electromechanical manufacturing technology, the sensor  devices can be applied healthy care of home care detection instrument to facilitate patient numerical monitoring .