Technical Name Semiconductor biosensor for portable, high sensitivity detection of infectious diseases
Project Operator Mobiosense Corp
Project Host 周聖燁
Summary
Mobiosense is focused on developing a semiconductor biosensor based on the field effect phenomenon, in which the electric current in the sensing layer of the semiconductor is influenced by external electric fields. In this case, Mobiosense’s sensor surface is modified with capture biomolecules (ex: antibodies, complementary DNA, etc), and will capture target biomolecules close to the sensor, carrying electric fields and producing the effect. By measuring the relative magnitude of electric signal change, we can calculate the biomarker concentration and correlate to a disease state. Mobiosense’s sensor is also designed to take advantage of existing full wafer processes in semiconductor sensors in Taiwan to provide high performing, low cost sensors
Scientific Breakthrough
Compared to traditional optical biodetection methods, Mobiosense's semiconductor biosensor does not require biochemical reactions to generate fluorescent or chemiluminescent signals, and can detect the presence of specific biomarkers by sensing the change in electric field brought upon by the charged biomolecules. Compared to other semiconductor biosensing technologies, our uniqe and patented nanoFET sensor design enable us achieve higher sensitivity towards weak electrical charges on biomolecules while employing standard full wafer processes to decrease cost and enable mass manufacturing
Industrial Applicability
Mobiosense's technology is applicable to industries with biosensing needs, such as healthcare, biomedical research, and pharmaceutical development.
Keyword Semiconductor Nanomaterial Protein Detection DNA Detection Disease Detection Point of Care Field Effect Transistor Biomolecule Detection Infectious Diseases Point of Care
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