Technical Name DRESSING COMPRISING ACTIVE COMPONENTS OF CENTELLA ASIATICA
Project Operator China Medical University
Summary
Provided is a dressing, comprising (a) a substrate layer and (b) an active component layer, which is a nanofiber layer and comprises: (b1) at least one of gelatin and collagen; (b2) polyvinyl alcohol (PVA); and (b3) at least one of asiaticoside and a Centella asiatica extract.
Scientific Breakthrough
藉由電紡技術製備出的明膠/聚乙烯醇結合積雪草活性成分之奈米纖維薄膜具有模仿細胞外基質的功能,使此奈米結構將積雪草活性成分-積雪草苷緩慢釋放至受傷的皮膚組織中促進皮膚內纖維母細胞增生,且明膠為天然之膠原蛋白熱變之產物,與皮膚接觸不易產生排斥性,隨後會被體液所分解,使此數材在幫助傷口修復完全時也能同時被組織降解後吸收,避免敷材在撕下時造成傷口的二度傷害。期望此新型數材能完全符合傷口治療的臨床應用,具有促進傷口癒合,缩短治癒時間的效果,以減輕患者所承受的痛苦。
Industrial Applicability
A dressing
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