The sub-nanometer gold administration can inactivate the endotoxin activity and diminish the inflammatory via blocking the lipid A of lipopolysaccharide, a bioactive bacterial debris for causing wound inflammation. In vitro and in vivo studies show that our gold nanocluster can reduce the cytokine secretions and improve infected wound repair.

1.高生物相容性
2.奈米金微粒藥物動力學時間長，半衰期長達17小時
3.降低發炎細胞激素濃度
4.縮短傷口發炎期
5.已在細胞及動物實驗獲得確效

This wound dressing technology based on gold sub-nanoclusters could be used as an endotoxin-inhibiting method to decrease pro-informatory factors. The invention might provide opportunities for the healthcare of aging society, which might prevent the problem of antibiotic resistance getting worse and reduce the medical expenses of chronic wounds.