Surface plasmon resonance (SPR) biosensor has many merits of high sensitivity, label-free detection, and real-time measurement. It is currently used as immunoassay and device for drug development, such as for affinity test of Biosimilar drug. Because of its high sensitivity, it has been recognized as the next-generation cancer cell assay. However, its high price tag and expansive chips are the barrier for such development. This patent proposed an innovative design of surface plasmon resonance biosensor. Utilizing a design of a free-form prism and a complementary optical system, the SPR biosensor has the potential to be developed as a medical device, which is compact, low cost, yet highly sensitive to answer the high demanding of modern medical detection.

表面電漿波生醫檢測器、微型、相對低價位、低價可拋式晶片、高靈敏度、大量測範圍、多流道晶片。
surface plasmon resonance biosensor, compactness, low-cost chips, high sensitivity, large dynamic range, multiple-channel detection

生物相似性藥物開發、蛋白質檢測、細菌抗藥性檢測、醫療血清蛋白檢測、高敏度水環境檢測器。