Technical Name Automatic fast-isolation machine for adipose-derived mesenchymal stem cells
Project Operator Kaohsiung medical university
Summary
Adipose-derived mesenchymal stem cells have been wildly applied in regenerative medicine. Several clinical trials have been studied, such as cornea, retina, cadiac muscle, bone, cartilage and skin with outstanding results. Autologous transplantation become a major consideration in the regeneration medicine by using stem cells. Traditional method to gain ADSCs needs twice or above operation procedures. In vitro amplification of ADSCs requires a GLP (Good Laboratory Practice)level lab and increases the chance to induce mutation or contamination through the environmental factors. Many factors protract the application of ADSCs in regeneration medicine. Our team develop an automatic fast isolation of ADSCs machine for instate. The total isolation and purification time is limited within 1.5 hours with sufficient number of ADSCs and 96% purity. It is suitable for application in regeneration medicine.
Scientific Breakthrough
特殊酵素配方專利,可快速從組織分離單細胞
新型組織均質機專利,配合酵素使用更加速分離效果且不傷害細胞
全自動細胞分離機專利,全自動無菌環境操作,減少人為或汙染風險
Industrial Applicability
為世界首創之脂肪間質幹細胞分離機,市面上雖有聲稱脂肪幹細胞分離機,均屬未經純化的脂肪組織內細胞,其中間質幹細胞含量約只有2%,並無法立即提供再生醫學的運用。本發明在未來的應用方面可快速、無細胞傷害性分離脂肪間質細胞,高產率無須經體外放大加上全自動分離機器設計,可產生一無菌、密閉、可調整型的脂肪間質幹細胞分離器在市面上並無相同功能的機器。提供未來脂肪間質幹細胞自體移植做再生醫學的應用。相對市面上的各種幹細胞銀行而言,可提供病患的另一種更安全的選擇。
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