Technical Name | Probing and manipulation of cell surface receptors with molecular scaffold | ||
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Project Operator | National Tsing Hua University | ||
Project Host | 王聖凱 | ||
Summary | Use synthetic biomolecule as scaffold to control ligand position at nanometer scale to probe and manipulate cell surface receptors |
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Scientific Breakthrough | Controlling the spatial presentation of ligands (drug molecules) at nanometer scale through modular assembly of synthetic molecular scaffold. |
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Industrial Applicability | Change the design and the use of drugs targeting cell surface receptors. |
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Keyword | receptor G protein-coupled receptor drug discovery molecular scaffold multivalent nanotechnology peptide macromolecule biomolecule membrane protein |