The detection of the embryo trophic growth factors in the single-embryo culture medium cannot be measured by conventional detection methods. Our team developed an embryo cytokine Meter with low sample requirement based on the digital microfluidic technology. This technology enables researchers to understand the conditions of different growth factors during the embryo development stage to improve IVF.

Currently, there is no equipment on the market for measuring embryo secretion factors in the embryo culture medium. Our technology can detect<40 min; sample volume< 1μL, and the limit of detection～2.1 pg/mL. While the existing method (e.g. ELISA kit, Flow CytoMetry ) needs a longer time and larger volume to detect. This device also has the potential to detect biomarkers for other clinical applications.

Currently, immunoassay technologies are unable to reach this degree. It is hoped that there will be a breakthrough contribution to the clinical application of artificial in vitro fertilization and even a further application to a variety of different biomarkers for simultaneous and rapid detection of other targets. Furthermore, to achieve a general digital microfluidic fluorescent immunoassay platform that helps early screening of the diseases.