Technical Name |
Antibody Profiling of Kawasaki Disease Using Escherichia coli Proteome Microarrays |
Project Operator |
CHANG GUNG MEDICAL FOUNDATION |
Project Host |
郭和昌 |
Summary |
We innovate the first laboratory method by using protein antibody array of Escherichia coli (E. Coli). We took only 125 pl of plasma ( means only 1/1,000,000 ml of blood extraction was needed, also means less than one drop of blood is need for identify Kawasaki Disease. More than 80% accuracy and excellent to outstanding discrimination results from this study may help clinician to diagnosis KD earlier and more precisely. |
Scientific Breakthrough |
We innovate the first laboratory method by using protein antibody array of Escherichia coli (E. Coli). We took only 125 pl of plasma ( means only 1/1,000,000 ml of blood extraction was needed, also means less than one drop of blood. The more than 80% accuracy and excellent to outstanding discrimination (> 0.8 AUC) results from this study may help clinician to diagnosis KD earlier and more precisely. |
Industrial Applicability |
It only took 125 pl of plasma, less than a drop of blood, in the focus array assays. |
Keyword |
Antibody Kawasaki disease E Coli heart disease prevention chip one drop of blood Children medicine rapid test one minute test precision medicine |