Technical Name |
Potential of Ambient Mass Spectrometry for Rapid DrugsToxin Identification |
Project Operator |
National Sun Yat-Sen University |
Project Host |
謝建台 |
Summary |
Through combining the cutting-edge technology of TD-ESI/MS to its comprehensive database library of toxicants, a fast-track toxicant analytical platforma set of standard operating procedures are developed that enables the emergency physicians to access correct toxicological information within a short turnaround timerescue the poisoned patients based on accurate laboratory data.
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Scientific Breakthrough |
Traditional mass spectrometric technologies such as LCMSGCMS must reduce matrix effect in order to accurately quantify. Therefore, it was needed to do complicated pretreatment prior to analysislead to be labortime-consuming. Compared to ambient mass spectrometry, it is more suitable for emergency medicine due to the fact it required only a few minutes to complete one analysis.
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Industrial Applicability |
This screening platform of ambient mass spectrometry is capable of identifying rapidly chemicals that are incorporated in its comprehensive toxicant database library. Its application in clinical toxicology through a set of standard operating procedures allows emergency physicians to obtain correct information in a short period of timetreat the poisoned patients in a precisetimely manner.
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Keyword |
Ambient Mass Spectrometry Laser Desorption-Electrospray Ionization Emergency management Rapid Screening Analysis Platform Point-of-Care Testing Untargeted Screening Psychoactive Drugs Abused Drugs |