| Technical Name | A legendary luminous nano-pearl | ||
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| Project Operator | National Cheng Kung University | ||
| Project Host | 葉晨聖 | ||
| Summary | The chromium-doped zinc gallate, ZnGa2O4:Cr3+, material is viewed as a long-lasting luminescent phosphor which can avoid tissue autofluorescence interference for in vivo imaging detection. The cubic ZGC revealed a specific accumulation in liver0.5 Gy used at the end of X-ray excitation was sufficient for imaging of deep seated hepatic tumors. |
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| Scientific Breakthrough | The chromium-doped zinc gallate, ZnGa2O4:Cr3+, material is viewed as a long-lasting luminescent phosphor which can avoid tissue autofluorescence interference for in vivo imaging detection. The cubic ZGC revealed a specific accumulation in liver0.5 Gy used at the end of X-ray excitation was sufficient for imaging of deep seated hepatic tumors. |
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| Industrial Applicability | The excellent long-lasting luminescence leads to significantly improve signal-to-noise in bioimaging. Using X-ray source has beyond the limitation of the penetration depth in tissue under in situ external excitation. These advantages let this nano-platform give the precision in diagnosis of diseases, e.g. malignant tumors, in the deep-seated organs in combination of optical navigation surgery. |
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| Keyword | in vivo imaging long-lasting luminescence (afterglow) X-ray nanoprobe clinical diagnosis imaging nano-biomedical imaging optical navigation surgery deep seated tissues imaging spatial and temporal precision biocompatibility | ||
- csyeh@mail.ncku.edu.tw
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