This project established a rapid next generation sequencing analysis system, to help clinicians to have next generation sequencing result  in time. It shortened the timeline to do sequencingthe time needed for analysis, to improve the quality of medical care.

We perform rapid whole exome sequencing to diagnose genetic  disease for pediatric critical patients. The major work aims on the establish the connection between clinicianlaboratory, shorten the timeline for sequencing, variant analysisprioritization ,interpretation. So that we can shorten the turnaround time of the test.

With the rapidly growing next generation sequencing technology, moremore challenges encountered. In this situation, the workflow established in this project will help the healthcare, especially intensive care system. It will change the medical care in the futureprovide precision medicine,become a model for critical care.