Cerebellar electroencephalography (cEEG) is a new technique in clinical electrophysiologymeasures cerebellar electric activities non-invasively. Classical EEG only records signals from cerebellar cortex. With animal-to-human translation in our tremor research project, we developed cEEG technique that may impact the research fieldclinical diagnosis in cerebellar disorders.

Abnormal cerebellar activities in patients with essential tremor (ET) were discovered in our tremor project,can be detected by the newly developed cEEG technology. To date, this cEEG-detectable abnormality is the firstthe only clinical biomarker of ET, a disease affecting 4 of adultsup to 20 of elderly population. Moreover, cEEG opens a window to clinical cerebellar researches.

cEEG, like classical EEG, is a clinical technique that is non-invasiveeasily performed. The market is huge, for cEEG-detectable abnormality is the only biomarker for essential tremor (ET) that affects 4 adults20 of elderly population. This does not include the upcoming clinical utilization in other cerebellar disordersalso cerebral disorders with associated cerebellar changes.