We have developed an ammonia sensor to detect ammonia in the parts-per-billion (ppb) regime. The detector is realized by using a novel organic semiconductor device. The invention patents in Taiwanthe USA have been approved. We demonstrated that breath ammonia(BA) concentration, measured by this sensor, was significantly positively correlated with blood urea nitrogen in chronic kidney disease(CKD) patients.

A reusable gas sensor capable of detecting ammonia in ppb regime was developed. With a prototype system to detect BA, the clinical research achieved a high correlation coefficient between BAblood urea nitrogen. Also, by improving structural configuration to enhance operational current, sensors were successfully integrated into embedded system achieving well-package prototype.

This technology integrates the strength of Taiwan’s semiconductor knowledgemedical resource. This developing medical equipment is expected to apply on self-monitoring in CKD patients, evaluation of dialysis adequacyearly detection of  CKD in high-risk populations, such as diabetic, hypertensive,aged patients. It is considered that this technique will benefit numerous people in the f